How to Perform "Cut&Run" Assays to Map Protein-DNA Interactions in Clinical Samples
Mapping the interactions between proteins and DNA is fundamental to understanding gene regulation, especially in the context of complex diseases like cancer and autoimmune disorders. For decades, Chromatin Immunoprecipitation Sequencing (ChIP-seq) was the gold standard for this task. However, ChIP-seq often requires millions of cells and suffers from high background noise due to the...
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