- Increased Nitric Oxide: Sexual stimulation triggers the release of nitric oxide, which is a chemical that helps to stimulate the production of cGMP. PDE5 inhibitors like sildenafil help prevent the rapid breakdown of cGMP, leading to increased levels of cGMP in the penis and prolonged relaxation of smooth muscles.
- Erection Facilitation: By inhibiting PDE5 and maintaining higher levels of cGMP, these medicines help the blood vessels in the penis to dilate, allowing more blood to flow into the erectile tissues. This increased blood flow makes it easier for men with ED to achieve and sustain an erection that is firm enough for sexual activity.
- Time Frame: Different PDE5 inhibitors have varying durations of action. For example, sildenafil and vardenafil typically work for around 4-5 hours, while tadalafil has a longer duration of action, up to 36 hours. This longer duration can allow for more spontaneity in sexual activity.
It's important to note that while ED medicines like Fildena 100 mg and Cenforce 150mg can be effective for many men, they are not a cure for impotence. They provide a temporary solution that helps facilitate erections when sexually aroused. Additionally, these medications may not work for everyone, and their effectiveness can vary depending on the underlying causes of ED.
Before using any ED medication, it's crucial to consult a healthcare professional. They can help determine if these medications are appropriate for your individual situation, consider any potential interactions with other medications you may be taking, and determine the correct dosage. It's also important to be aware of potential side effects and to follow your doctor's guidance for safe use.
ED medicines should be considered as part of a comprehensive approach to managing erectile dysfunction, which may include lifestyle changes, addressing underlying health conditions, and open communication with your healthcare provider and partner.
